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CD spectra of r(G2C4)4 and proposed hairpin adopted at pH 4.5. (a) CD spectra of r(G2C4)4 with pH ranging from 7.0 to 4.5. All CD spectra were acquired at 25 °C and concentration of 100 µM per strand. Arrows represent the direction of change in pH. (b) Schematic presentation of hairpin formed by r(G2C4)4 at pH 4.5 and 25 °C.
