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Light inducible epigenome editing. (a) The LITE and epiTALE system. Light induces dimerization of CRY2 and CIB1 to direct epigenome modifiers to TALE-targeting sites for epigenome editing. (b) The CASANOVA system used light responsive LOV2-AcrIIA4 to target dCas-p300 for H3K27ac editing.
