Table 2.
The KEGG Pathway Enrichment Analysis for the DEGs of Different Groups of GSE95849
| Category | Term | Count | % | P-value |
|---|---|---|---|---|
| DM v CN | ||||
| KEGG_PATHWAY | hsa04060:Cytokine-cytokine receptor interaction | 24 | 0.57859 | 1.44E-05 |
| hsa04620:Toll-like receptor signaling pathway | 10 | 0.24108 | 0.00606 | |
| hsa04640:Hematopoietic cell lineage | 9 | 0.21697 | 0.00737 | |
| hsa03320:PPAR signaling pathway | 8 | 0.19286 | 0.00753 | |
| hsa04062:Chemokine signaling pathway | 12 | 0.2893 | 0.04589 | |
| DPN v CN | ||||
| KEGG_PATHWAY | hsa04620:Toll-like receptor signaling pathway | 18 | 0.142 | 0.00431 |
| hsa04210:Apoptosis | 16 | 0.12622 | 0.00568 | |
| hsa04640:Hematopoietic cell lineage | 15 | 0.11833 | 0.01226 | |
| hsa00020:Citrate cycle (TCA cycle) | 8 | 0.06311 | 0.01298 | |
| hsa04621:NOD-like receptor signaling pathway | 12 | 0.09467 | 0.01361 | |
| hsa04062:Chemokine signaling pathway | 25 | 0.19722 | 0.02449 | |
| hsa04010:MAPK signaling pathway | 32 | 0.25245 | 0.04111 | |
| hsa04662:B cell receptor signaling pathway | 12 | 0.09467 | 0.04898 | |
| DPN v DM | ||||
| KEGG_PATHWAY | hsa04621:NOD-like receptor signaling pathway | 15 | 0.19214 | 1.56E-06 |
| hsa04010:MAPK signaling pathway | 31 | 0.39708 | 2.19E-05 | |
| hsa04722:Neurotrophin signaling pathway | 16 | 0.20494 | 0.00127 | |
| hsa04662:B cell receptor signaling pathway | 11 | 0.1409 | 0.00401 | |
| hsa04062:Chemokine signaling pathway | 19 | 0.24337 | 0.00573 | |
| hsa04640:Hematopoietic cell lineage | 11 | 0.1409 | 0.01057 | |
| hsa04620:Toll-like receptor signaling pathway | 12 | 0.15371 | 0.01205 | |
| hsa00020:Citrate cycle (TCA cycle) | 6 | 0.07685 | 0.01803 | |
| hsa04060:Cytokine-cytokine receptor interaction | 21 | 0.26899 | 0.03948 |
Abbreviation: KEGG, Kyoto Encyclopedia of Genes and Genomes.