Table 1.
Patient ID | Diagnosis | Age at Surgery (Years) | Sex | Surgical Procedure | Grade | Resection Status | Location | Size (mm) | Background Pathology |
---|---|---|---|---|---|---|---|---|---|
PIN 062 | Islet cell carcinoma (ICC) | 66.1 | M | Whipple’s | Moderately differentiated | - | - | 15 | - |
PIN 065 | Invasive ductal adenocarcinoma (PDAC) | 77.4 | F | Whipple’s | Moderately differentiated | - | - | 50 | - |
PIN 080 | Invasive adenocarcinoma | 70.6 | M | Whipple’s | Moderately differentiated | - | - | 8 | - |
PIN 082 | Intraductal papillary mucinous neoplasm (IPMN) | 63.8 | M | Total Pancreatectomy Incl Spleen | Low- and high-grade dysplasia | - | - | 60 | - |
PIN 089 | Invasive ductal adenocarcinoma | 45.9 | F | Distal Pancreas | Moderately differentiated | - | - | 35 | - |
PIN 091 | Invasive ductal adenocarcinoma | 64.5 | M | Median Pancreatectomy | Moderately invasive | - | - | 21 | PanIN 2 and focal chronic pancreatitis |
PIN 099 | Invasive ductal adenocarcinoma | 63.0 | F | Whipple’s | Poorly differentiated | R0 | Pancreatic Head | 17 | Pancreatic intraepithelial neoplasia, low-grade (PanIN1) and marked chronic pancreatitis |
PIN 102 | Cholangiocarcinoma | 61.8 | M | Whipple’s | Poorly differentiated | - | - | 23 | - |
PIN 112 | Invasive ductal adenocarcinoma | 79.7 | M | Distal Pancreas | Moderate differentiation | - | - | 20 | Chronic pancreatitis |
PIN 113 | Poorly differentiated adenocarcinoma with anaplastic and signet ring | 74.7 | M | Distal Pancreas | Poorly differentiated | - | - | 145 | - |
PIN 115 | Invasive ductal adenocarcinoma, moderately differentiated | 72.8 | F | Distal Pancreatectomy | Moderately differentiated | - | - | 35 | Chronic pancreatitis and PanIN of the main pancreatic duct |
PIN 116 | Invasive ductal carcinoma | 62.4 | M | Distal Pancreas | Poorly differentiated | - | Pancreatic Tail | 60 | Prominent associated chronic pancreatitis |
PIN 120 | Invasive ductal adenocarcinoma | 65.1 | M | Whipple’s | Moderately differentiated | - | Head of Pancreas | 14 | The pancreatic parenchyma shows PanIN3 and focal chronic pancreatitis |
PIN 127 | Invasive moderately differentiated adenocarcinoma | 72.7 | M | Whipple’s | Moderately differentiated | - | - | 48 | PanIN Ib is noted in the pancreas |
PIN 132 | Metastatic renal cell carcinoma (RCC) | 71.2 | M | Whipple’s | - | - | - | 25 | - |
PIN 135 | Neuroendocrine tumour (NET) | 70.9 | M | - | - | - | - | 13 | - |
PIN 137 | Invasive ductal adenocarcinoma | 68.9 | M | Whipple’s | Moderately differentiated | Uncinate Process | 30 | Chronic pancreatitis | |
PIN 138 | Invasive adenocarcinoma, intestinal type | 60.1 | M | Whipple’s | Moderately differentiated | R0 | - | 19 | Stomach with chronic gastritis, mild activity and focal chronic pancreatitis |
PIN 139 | Invasive ductal adenocarcinoma with squamous differentiation | 70.8 | M | Pancreaticoduodenectomy (Whipple’s resection) | Poorly differentiated | - | Uncinate Process | 30 | - |
PIN 140 | Invasive ductal carcinoma | 63.5 | M | Pancreaticoduodenectomy, Whipple’s procedure | Moderate | R0 | Pancreatic Head | 32 | Invasive tumour arises in association with an IPMN which displays intestinal differentiation and contains moderate dysplasia. The invasive tumour present is pancreatico-biliary type (non-mucinous). Focal chronic pancreatitis and chronic inactive gastritis also noted |
PIN 141 | Invasive ductal adenocarcinoma | 82.7 | M | Whipple’s | Poorly differentiated | - | Pancreatic Head | 35 | Chronic pancreatitis |
PIN 145 | Post chemoradiotherapy - tumour presumed necrotic | 71.2 | M | Whipple’s | - | - | - | 32 (50 mm on pre-neoadj CT) | - |
PIN 148 | invasive ductal adenocarcinoma | 62.9 | F | Distal Pancreatectomy | Poorly differentiated | - | - | 15 | - |
PIN 160 | Invasive ductal adenocarcinoma, moderately differentiated | 77.4 | F | Whipple’s | Moderately differentiated | - | - | 25 | Extensive associated chronic pancreatitis |
PIN 161 | Invasive ductal adenocarcinoma | 61.3 | M | Whipple’s | Moderately differentiated | - | Uncinate Process/Pancreatic Head | High-grade PanIN | |
PIN 165 | Invasive ductal carcinoma | 57.4 | F | Whipple’s | Poorly differentiated | - | Pancreatic Head and Uncinate Process | 35 | - |
PIN 175 | IPMN/NET | 63.1 | M | Whipple’s | - | - | - | 27 | - |
PIN 190 | Invasive ductal adenocarcinoma | 71.8 | M | Whipple’s | Poorly differentiated | - | Pancreatic Head | 25 | - |
PIN 191 | Ductal adenocarcinoma post neo-adjuvant chemotherapy | 70.3 | F | Central and Distal Pancreas | Moderately differentiated, entrapped within a densely fibrotic stroma showing chronic inflammation and evidence of treatment effect | - | - | - | - |
PIN 194 | No evidence of residual tumour—complete pathology response | 71.6 | F | Whipple’s | - | - | - | 0 | - |
PIN 199 | Invasive ductal adenocarcinoma neo-adjuvant chemotherapy and radiotherapy | 62.2 | M | Distal Pancreatectomy with Splenectomy | Moderately differentiated | - | - | 15 | PanIN grade 3 |
PIN 205 | Invasive ductal carcinoma | 63.6 | F | Pancreatic Duodenectomy (Whipple’s Resection) | Moderately differentiated | R1 | Pancreatic Head | 20 | PanIN, chronic pancreatitis |
PIN 210 | Well-differentiated neuroendocrine tumour (NET) | 65.4 | M | Whipple’s Resection) Pancreaticoduodenectomy | G1 (1 mitoses/10 hpf, Ki67 index = 5%) | - | - | - | - |
PIN 211 | Invasive ductal adenocarcinoma | 80.0 | M | Whipple’s/Pancreatico-duodenectomy: | Well differentiated | R1 | Pancreatic Head | 25 | Chronic pancreatitis Pancreatic divisum |
PIN 212 | Mucinous cystic neoplasm | 63.4 | F | Distal Pancreas and Spleen | - | - | - | 100 | - |
PIN 213 | Invasive adenocarcinoma/cholangiocarcinoma | 70.6 | F | Pancreatico-duodenectomy: Whipple’s | Moderately differentiated | R0 | Distal Common Bile Duct (Intra-Pancreatic) | 20 | PanIN 1b: Chronic pancreatitis and chronic cholecystitis, |
PIN 214 | Well-differentiated neuroendocrine tumour | 79.2 | F | Distal Pancreatectomy with Spleen | G2 (3 mitoses/10 hpf, Ki-67 > 5–20%) | R0 | - | 60 | - |
PIN 218 | Well-differentiated neuroendocrine tumour (NET) | 47.7 | F | Pancreaticoduodenectomy (Whipple’s Resection) | G1 (<2 mitoses/10 hpf). | R1 | Head and Neck of Pancreas | - | - |
PIN 222 | Invasive ductal carcinoma | 64.5 | M | Pancreaticoduodenectomy (Whipple’s Resection) | Moderately differentiated | R0 | Pancreatic Head | Chronic pancreatitis, chronic cholecystitis and cholelithiasis | |
PIN 226 | Invasive ductal adenocarcinoma | 71.6 | F | Pancreaticoduodenectomy (Whipple’s Resection) | Moderately differentiated | R0 | - | 40 | - |
PIN 228 | Invasive ductal adenocarcinoma | 77.1 | M | Pancreaticoduodenectomy (Whipple’s Resection) | Moderately differentiated | R0 | - | - | - |
PIN 233 | Invasive ductal adenocarcinoma | 73.0 | F | Pancreaticoduodenectomy (Whipple’s Resection) | Moderately differentiated | R0 | Pancreatic Head | - | - |
PIN 238 | Neuroendocrine tumour | 40.7 | M | Whipple’s | - | - | - | - | - |
PIN 239 | GIST* | 57.6 | F | - | - | - | - | - | - |
PIN 266 | Cholangiocarcinoma | 57.0 | F | Whipple’s | - | - | - | - | - |
PIN 268 | Invasive ductal adenocarcinoma | 57.3 | M | Whipple’s | Poorly differentiated | R1 | - | - | Chronic Pancreatitis |
PIN 277 | Adenocarcinoma | 69.2 | M | Pancreaticoduodenectomy (Whipple’s Resection) | - | R0 | - | - | PanIN Grade 1 |
PIN 291 | Adenocarcinoma, pancreaticobiliary type | 56.5 | F | Pancreaticoduodenectomy (Whipple’s Resection) | - | R1 | - | - | - |
* GIST = Gastro-intestinal stromal tumour; “-“ = information not available