Table 5.
The number of gene changes detected across the sample types, normal vs. tumour, tumour vs. F1 and triple comparison of normal vs. tumour vs. F1. All gene changes reported were statistically significant (p ≤ 0.05). Genes that were 2-fold or greater increased were investigated further.
Comparison | Criteria p ≤ 0.05 | Number of Genes Changed |
---|---|---|
Normal vs. tumour | 1.5-fold increase | 1019 |
2-fold increase | 413 | |
1.5-fold decrease | 394 | |
2-fold decrease | 116 | |
Tumour vs. F1 | 1.5-fold increase | 1670 |
2-fold increase | 491 | |
1.5-fold decrease | 2145 | |
2-fold decrease | 1312 | |
Normal vs. tumour vs. F1 | 1.5-fold increase | 274 |
2-fold increase | 89 | |
1.5-fold decrease | 94 | |
2-fold decrease | 33 | |
Normal vs. tumour vs. F1 | 1.5-fold increase in T (vs. N) and 1.5-fold decrease in F1 (vs. T) | 147 |
1.5-fold decrease in T (vs. N) and 1.5-fold increase in F1 (vs. T) | 9 |