Table 6.
Top 20 differentially expressed genes upregulated in a comparison of tumour vs. normal samples, ordered by fold change.
| Gene Symbol | Tumour Avg (log2) | Normal Avg (log2) | Tumour SD | Normal SD | Fold Change | p-value |
|---|---|---|---|---|---|---|
| SLC6A14 | 7.6 | 3.1 | 1.9 | 1.9 | 22.8 | 4.00 × 10−4 |
| TSPAN1 | 7.8 | 4.5 | 1.0 | 1.4 | 9.5 | 2.97 × 10−5 |
| TMPRSS4 | 7.2 | 3.9 | 1.2 | 1.3 | 9.5 | 2.00 × 10−4 |
| MUC13 | 8.9 | 5.6 | 1.6 | 1.7 | 9.4 | 7.00 × 10−4 |
| SLPI | 8.9 | 6.1 | 0.9 | 1.8 | 6.9 | 6.00 × 10−4 |
| SERPINB5 | 5.3 | 2.5 | 0.9 | 1.0 | 6.8 | 8.84 × 10−5 |
| NQO1 | 7.9 | 5.3 | 1.0 | 1.6 | 6.4 | 8.45 × 10–5 |
| HIST1H2BM | 6.2 | 3.5 | 1.3 | 1.7 | 6.4 | 6.10 × 10–3 |
| TOP2A | 6.4 | 3.7 | 0.7 | 1.4 | 6.4 | 2.00 × 10–4 |
| FERMT1 | 7.6 | 4.9 | 1.1 | 0.9 | 6.4 | 3.00 × 10–4 |
| GALNT5 | 6.5 | 4.0 | 1.7 | 1.2 | 5.8 | 3.89 × 10–2 |
| PLS1 | 8.4 | 6.1 | 0.9 | 0.9 | 5.3 | 7.00 × 10–4 |
| TSPAN8 | 8.0 | 5.6 | 0.6 | 1.2 | 5.2 | 3.00 × 10–4 |
| TMEM45B | 6.9 | 4.5 | 0.8 | 1.0 | 5.0 | 4.00 × 10–4 |
| AGR2 | 5.7 | 3.4 | 1.4 | 1.3 | 5.0 | 1.50 × 10–3 |
| LIPH | 8.1 | 5.9 | 1.1 | 1.3 | 4.9 | 3.00 × 10–4 |
| KRT23 | 7.5 | 5.3 | 0.6 | 1.3 | 4.5 | 8.80 × 10–5 |
| FAM83B | 6.8 | 4.7 | 1.2 | 1.3 | 4.5 | 5.00 × 10–4 |
| TPX2 | 5.1 | 3.0 | 0.9 | 1.1 | 4.4 | 3.40 × 10–3 |
| C19orf33 | 8.2 | 6.1 | 0.6 | 1.4 | 4.3 | 1.65 × 10–2 |