Figure 3.

Venn diagram of master regulators identified. Native MR—master regulators identified upon the interaction (incubation) of cultured monocyte-derived macrophages with native LDL. Ath MR—master regulators identified upon the interaction (incubation) of cultured monocyte-derived macrophages with naturally occurring LDL isolated from the blood of atherosclerotic patients. Latex MR—master regulators identified upon the interaction (incubation) of monocyte-derived macrophages with latex beads. The total number of identified up- and down-regulated master regulators was shown in brackets (gene nomenclature can be found in the Supplementary Materials section). Darker colors indicated regulation of genes which coincided (diagram overlaps).