Table 3.
Matching master regulators for LDL and latex beads.
| Qty | Gene Symbol | Gene Name | ||
|---|---|---|---|---|
| naturally occurring LDL | up | 11 | EP300 | E1A binding protein p300 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | |||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | |||
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | |||
| NCF2 | neutrophil cytosolic factor 2 | |||
| PIK3R5 | phosphoinositide-3-kinase regulatory subunit 5 | |||
| PRKCD | protein kinase C, delta | |||
| PTGES | prostaglandin E synthase | |||
| RAD23A | RAD23 homolog A, nucleotide excision repair protein | |||
| RIPK2 | receptor interacting serine/threonine kinase 2 | |||
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | |||
| dn | 9 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 | |
| CDC42 | cell division cycle 42 | |||
| DUSP7 | dual specificity phosphatase 7 | |||
| GSK3B | glycogen synthase kinase 3 beta | |||
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | |||
| NCF1 | neutrophil cytosolic factor 1 | |||
| TAOK1 | TAO kinase 1 | |||
| TGFB2 | transforming growth factor beta 2 | |||
| TRAF6 | TNF receptor associated factor 6 | |||
| desialylated LDL | up | 10 | EP300 | E1A binding protein p300 |
| CASP2 | caspase 2 | |||
| DUSP5 | dual specificity phosphatase 5 | |||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | |||
| PIK3R5 | phosphoinositide-3-kinase regulatory subunit 5 | |||
| PTGES | prostaglandin E synthase | |||
| PRKCD | protein kinase C, delta | |||
| PRKCB | protein kinase C, beta | |||
| RAD23A | RAD23 homolog A, nucleotide excision repair protein | |||
| RIPK2 | receptor interacting serine/threonine kinase 2 | |||
| dn | 9 | DUSP7 | dual specificity phosphatase 7 | |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | |||
| MAP2K5 | mitogen-activated protein kinase kinase 5 | |||
| MAP2K7 | mitogen-activated protein kinase kinase 7 | |||
| NCF1 | neutrophil cytosolic factor 1 | |||
| TGFB2 | transforming growth factor beta 2 | |||
| TGFB3 | transforming growth factor beta 3 | |||
| TRADD | TNFRSF1A-associated via death domain | |||
| TRAF6 | TNF receptor associated factor 6 | |||
| acetylated LDL | up | 4 | NCF2 | neutrophil cytosolic factor 2 |
| PRKCD | protein kinase C, delta | |||
| PTGES | prostaglandin E synthase | |||
| SGK1 | serum/glucocorticoid regulated kinase 1 | |||
| dn | 14 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 | |
| CASP8 | caspase 8 | |||
| DUSP1 | dual specificity phosphatase 1 | |||
| DUSP16 | dual specificity phosphatase 16 | |||
| GSK3B | glycogen synthase kinase 3 beta | |||
| HDAC3 | histone deacetylase 3 | |||
| IL1A | interleukin 1 alpha | |||
| MAP2K1 | mitogen-activated protein kinase kinase 1 | |||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | |||
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | |||
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 | |||
| TAOK1 | TAO kinase 1 | |||
| TRADD | TNFRSF1A-associated via death domain | |||
| TRAF6 | TNF receptor-associated factor 6 | |||
| oxidized LDL | up | 7 | CASP2 | caspase 2 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | |||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | |||
| NCF2 | neutrophil cytosolic factor 2 | |||
| PRKCB | protein kinase C, beta | |||
| RAD23A | RAD23 homolog A, nucleotide excision repair protein | |||
| SGK1 | serum/glucocorticoid regulated kinase 1 | |||
| dn | 13 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 | |
| CDC42 | cell division cycle 42 | |||
| DUSP1 | dual specificity phosphatase 1 | |||
| DUSP16 | dual specificity phosphatase 16 | |||
| GSK3B | glycogen synthase kinase 3 beta | |||
| HDAC3 | histone deacetylase 3 | |||
| KRAS | Kirsten rat sarcoma viral oncogene homolog | |||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | |||
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | |||
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | |||
| NCF1 | neutrophil cytosolic factor 1 | |||
| TAOK1 | TAO kinase 1 | |||
| TRAF6 | TNF receptor associated factor 6 |
Matching master regulators were listed in blue.