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. 2019 Nov 14;217(1):e20191397. doi: 10.1084/jem.20191397

Table 2. Investigational drugs targeting IL-17 in indications of interest.

INN/Code Target Construct Indicationa
Bimekizumab IL-17A/F Humanized mAb Pso, PsA, AS
M1095 IL-17A/F Nanobody Pso, PsA
ALX-0761 IL-17A/F Nanobody Pso, PsA
BCD-085 IL-17A mAb Pso, PsA
COVA322 IL-17A/TNF Bispecific mAb Pso, PsA

INN, international nonproprietary names; Pso, psoriasis.

a

In clinical trials/planned.