Table 2. Investigational drugs targeting IL-17 in indications of interest.
INN/Code | Target | Construct | Indicationa |
---|---|---|---|
Bimekizumab | IL-17A/F | Humanized mAb | Pso, PsA, AS |
M1095 | IL-17A/F | Nanobody | Pso, PsA |
ALX-0761 | IL-17A/F | Nanobody | Pso, PsA |
BCD-085 | IL-17A | mAb | Pso, PsA |
COVA322 | IL-17A/TNF | Bispecific mAb | Pso, PsA |
INN, international nonproprietary names; Pso, psoriasis.
In clinical trials/planned.