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. 2019 Oct 23;217(1):e20182325. doi: 10.1084/jem.20182325

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© 2019 Liu et al.

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Figure 2. — GEC C1galt1^−/− mice develop spontaneous gastric cancer. (A) Gross morphology and H&E staining of murine stomach. Arrow points to a gastric tumor. Inset: Magnified images of boxed regions on left. Scale bars, 1 cm (gross morphology); 200 µm (tiling images); 50 µm (left inset); 12.5 µm (right inset). a, antrum; c, corpus; d, duodenum; f, forestomach. (B) Mean tumor volume (mean ± SD). (C) Tumor incidence (percentage of mice with tumors). (D) H&E staining of antrum. Arrows indicate carcinoma. Scale bars, 125 µm. (E) Incidence of gastric carcinoma. Data are representative of at least two independent experiments (mean ± SD; n = 8–10 mice/group for A, C, and D; n = 4–5 mice/group for B). *, P < 0.05.