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. 2019 Oct 23;217(1):e20182325. doi: 10.1084/jem.20182325

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© 2019 Liu et al.

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Figure 8. — Truncated O-glycans and inflammasome activation are associated with gastritis and gastric cancer in human patients. (A) IHC for Tn-antigen in human gastric tissue sections. Scale bars, 50 µm (upper panel) and 20 µm (inset). (B) IHC for Casp1 in human gastric tissue sections. Arrows indicate cytoplasmic staining, and arrowheads indicate nuclear staining. (C) Frequency of low versus high Tn expression status (defined in Materials and methods) in tissue in relation to disease status. (D) Western blot analysis of CASP1 expression in human gastric cancer tissue samples. Each lane represents one gastric cancer tissue sample. Exp., exposure.