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. 2020 Feb 7;25(3):724. doi: 10.3390/molecules25030724

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The anti-inflammatory effects of curcumin were evaluated through measurement of Tumour Necrosis Factor alpha (TNF-α), Interleukin 6 (IL-6), and C-reactive protein (CRP): BaP -induced group showed the levels of TNF-α and IL-6 were found to be substantial increased as compared with the control group (p < 0.05). However, production of TNF-α and IL-6 and were significantly decreased in the BaP plus curcumin treated group (p < 0.05). The level of CRP was increased in the BaP-treated group as compared to control group as well as co-administration of curcumin (50 mg/kg) with BaP (50 mg/kg), but difference was statically insignificant (p > 0.05).