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. 2020 Jan 31;21(3):956. doi: 10.3390/ijms21030956

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Figure A1 — Comparison of α-Gal A activity of GLA gene variants without and with the addition of DGJ between the in-house assay and GLP-validated assay [14]. (a) GLA gene variants that were classified as amenable according to in-house data. (b) GLA gene variants that were classified as non-amenable according to in-house data. GLA variants were ordered with respect to their positions on the amino-acid sequence. Variants with no associated bar had no quantifiable α-Gal A activity without or with the addition of DGJ.