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. 2020 Jan 27;21(3):823. doi: 10.3390/ijms21030823

Figure 1.

Figure 1

The role of syndecan-4 and Rac1 (Ras-related C3 botulinum toxin substrate 1) in random, two-dimensional migration of myoblasts. The total length of movement (A), the vectorial distance (real displacement of the cells) (B), the maximum distance from the starting point (C), the average cell speed (D), and the maximum speed (E) of the cells are depicted in non-transfected, scrambled, and syndecan-4 silenced (shSDC4#1, shSDC4#2) C2C12 myoblast cells either without or with NSC23766 (Rac1 inhibitor) treatment. Schematic representation of the total path, vectorial distance, and maximum distance of the movement (F). The total duration of live cell microscopy: 18 h, frame rate: 3/1 h; n = 4 independent experiments; 62–114 cells/cell line; and 6–8 fields of view/experiment. Data are reported means of the independent experiments + SEM; **** p < 0.0001; *** p < 0.001; ** p < 0.01; * p < 0.05.