Table 3.
Difference in terms of effort dependent variables from maximal tests according to phenotype.
| Emphysematous (n=18) | Non-emphysematous (n=13) | p | |
|---|---|---|---|
| VO2 peak absolute, L | 1.159 (0.873-1.309) | 1.293 (1.007-1.581) | 0.242 |
| VO2 peak absolute, ml/min/kg | 15.9 (13.2-19.0) | 19.8 (12.9-21.6) | 0.312 |
| VO2 peak, %predicted | 63 (52-78) | 85 (63-95) | 0.051 |
| Work peak absolute, W | 72 (43-82) | 89 (60-107) | 0.106 |
| Work peak, %predicted | 51 (43-70) | 72 (69-86) | 0.016* |
| Respiratory Exchange Ratio at peak | 1.08 (0.99-1.16) | 1.11 (0.99-1.20) | 0.594 |
| Heart rate peak, %predicted | 86 (71-94) | 89 (76-94) | 0.755 |
| Oxygen pulse peak absolute, ml/beat | 9 (8.1-10.1) | 10.0 (8.0-11.7) | 0.346 |
| Oxygen pulse peak, %pred | 76 (71-93) | 98 (78-114) | 0.124 |
| Breathing reserve, % | 9 (1-20) | 26 (7-37) | 0.106 |
| Ventilation peak absolute, L | 44.3 (35.4-54.3) | 40.0 (35.9-56.4) | 0.798 |
| VE/VCO2 nadir, L/L | 36 (33-43) | 32 (29-34) | 0.004* |
| PET CO2, mmHg | 33 (30-35) | 36 (34-41) | 0.012* |
| Tidal volume peak, L | 1.222 (0.969-1.447) | 1.241 (1.017-1.425) | 1.000 |
| Breathing frequency peak, breaths/min | 37 (30-40) | 35 (31-39) | 0.567 |
| Δ Tidal volume peak-rest, L | 0.432 (0.297-0.571) | 0.604 (0.416-0.722) | 0.125 |
| Δ Breathing frequency peak-rest, breaths/min | 11 (8-20) | 11 (7-18) | 0.798 |
| VTpeak/FEV1 | 0.92 (0.80-1.02) | 0.80 (0.73-0.94) | 0.293 |
| VTpeak/FVC | 0.44 (0.39-0.51) | 0.48 (0.41-0.55) | 0.125 |
VE, ventilation; VO2, oxygen consumption; VCO2, carbon dioxide output; VE, ventilation; PETCO2, end tidal pressure for carbon dioxide; VT, tidal volume; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.
*p<0.05.