Table 2.
Angiographic and echocardiographic characteristics of the whole study group of patients with ST-segment elevation myocardial infarction and two patient subgroups, which were found with or without left ventricular systolic dysfunction 6 months after discharge.
| Variable | Whole Study Group (n = 199) | Patients with LVSD 6 Months after Discharge (n = 35) | Patients without LVSD 6 Months after Discharge (n = 164) | p-Value between Patients with or without LVSD |
|---|---|---|---|---|
| Angiographic indices: | ||||
| LAD/non-LAD n (%) | 92 (46.2)/107 (53.8) | 32 (91.4)/3 (8.6) | 60 (36.6)/104 (63.4) | <0.001 |
| TIMI 3 flow pre-PCI n (%) | 55 (27.6) | 3 (8.6) | 52 (31.7) | 0.035 |
| TIMI 3 flow post-PCI n (%) | 185 (93.0) | 29 (82.9) | 156 (95.1) | 0.02 |
| TMPG 3 post-PCI n (%) | 92 (46.2) | 15 (42.9) | 77 (47.0) | 0.659 |
| Multivessel coronary disease n (%) | 119 (59.8) | 22 (62.9) | 97 (59.1) | 0.638 |
| Abciximab use n (%) | 50 (25.1) | 15 (42.9) | 35 (21.3) | 0.007 |
| Intracoronary stents n (%) | 197 (99.0) | 35 (100.0) | 162 (98.8) | 0.197 |
| Echocardiographic indices at discharge: | ||||
| LVEDd (mm) | 49.0 (45.0–53.0) | 53.0 (52.0–57.0) | 48.0 (45.0–52.0) | <0.001 |
| LVESd (mm) | 34.0 (30.0–37.0) | 38.0 (36.0–45.0) | 33.0 (30.0–35.0) | <0.001 |
| LVEDVI (mL/m²) | 48.4 (44.2–60.6) | 60.4 (53.9–69.6) | 48.6 (43.0–57.9) | <0.001 |
| LVESVI (mL/m²) | 26.8 (23.1–34.9) | 37.7 (33.4–43.8) | 25.8 (22.9–30.7) | <0.001 |
| LVEF (%) | 45.0 (40.0–49.7) | 36.0 (33.5–40.0) | 46.0 (42.5–50.0) | <0.001 |
| WMSI (pts) | 1.5 (1.38–1.75) | 1.81 (1.75–1.94) | 1.44 (1.38–1.69) | <0.001 |
| S′ (cm/s) | 7.0 (6.1–8.1) | 5.9 (5.1–6.8) | 7.2 (6.4–8.4) | <0.001 |
| DT (ms) | 155.0 (145.0–185.0) | 145.0 (135.0–155.0) | 160.0 (150.0–190.0) | <0.001 |
| E/E′ (−) | 10.3 (8.4–12.6) | 11.8 (9.6–13.9) | 10.1 (8.2–12.0) | 0.005 |
| Echocardiographic indices 6 months after discharge: | ||||
| LVEDd (mm) | 50.0 (46.0–54.0) | 55.0 (50.0–56.0) | 48.5 (45.5–53.0) | <0.001 |
| LVESd (mm) | 34.0 (31.0–37.0) | 39.0 (35.0–44.0) | 33.0 (31.0–36.0) | <0.001 |
| LVEDVI (mL/m²) | 57.4 (48.8–68.6) | 76.9 (68.1–83.1) | 54.5 (43.2–65.0) | <0.001 |
| LVESVI (mL/m²) | 29.3 (24.8–39.0) | 48.2 (40.9–56.4) | 27.7 (24.1–33.6) | <0.001 |
| LVEF (%) | 46.0 (42.3–52.0) | 36.0 (34.0–38.6) | 47.7 (44.2–52.5) | <0.001 |
| WMSI (pts) | 1.44 (1.31–1.63) | 1.88 (1.69–1.94) | 1.38 (1.31–1.5) | <0.001 |
| S′ (cm/s) | 7.0 (6.1–8.1) | 5.6 (4.8–6.9) | 7.1 (6.3–8.2) | <0.001 |
| DT (ms) | 170.0 (155.0–195.0) | 150.0 (135.0–190.0) | 175.0 (155.0–200.0) | <0.001 |
| E/E′ (−) | 9.5 (8.0–11.7) | 13.1 (9.7–16.3) | 9.1 (7.9–10.8) | <0.001 |
Data represent median values with corresponding interquartile range (in parentheses). Abbreviations: DT—deceleration time of early transmitral flow; E—peak velocity of early transmitral flow; E′—average peak early diastolic mitral annular velocity; LAD—infarct-related left descending artery; LVEDd—left ventricular end-diastolic diameter; LVEDVI—left ventricular end-diastolic volume index; LVEF—left ventricular ejection fraction; LVESd—left ventricular end-systolic diameter; LVESVI—left ventricular end-systolic volume index; LVSD—left ventricular systolic dysfunction; PCI—primary percutaneous coronary intervention; S′—average peak systolic mitral annular velocity; STEMI—ST-segment elevation myocardial infarction; TIMI—Thrombolysis in Myocardial Infarction score; TMPG—TIMI Myocardial Perfusion Grade; WMSI—wall motion score index.