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. 2020 Jan 30;92:100576. doi: 10.1016/j.curtheres.2020.100576

Table 1.

Interpretation of combination index values in drug combinations.8

Combination index value Interpretation
<0.1 Very strong synergism
0.1–0.3 Strong synergism
0.3–0.7 Synergism
0.7–0.85 Moderate synergism
0.85–09 Slight synergism
0.9–1.1 Nearly additive
1.1–1.45 Slight to moderate antagonism
1.45–3.3 Antagonism
3.3–10 Strong antagonism
>10 Very strong antagonism