Table 2.
The half-maximal inhibitory concentration (IC50) and selectivity index (SI) values of 1,3,6-trihydroxy-4,5,7-trichloroxanthone (TTX) and doxorubicin against Raji or Vero cell lines.*
| Compound | IC50 value (µM) |
SI value† | |
|---|---|---|---|
| Raji | Vero | ||
| TTX | 15.948 (3.101) | 256.288 (25.617) | >76.57 |
| Doxorubicin | 25.432 (1.417) | 149.917 (28.277) | 5.89 |
⁎
Values are the mean (SD) of 3 experiments. Viability of Raji or Vero cells was evaluated after 24 hours of TTX or doxorubicin individual treatment and evaluated using the MTT method.
†
Selective if >3.23