Table 5.

The atom components and amino acid residues involved in the hydrogen bonds formed between Raf-1 and 1,3,6-trihydroxy-4,5,7-trichloroxanthone (TTX).

Ligand components^*	Amino acid residues of Raf-1 protein
H of OH (C-1)	O atom (C=O) of Cys⁴²⁴
H of OH (C-1)	O atom (C=O) of Gly⁴²⁶
O of OH (C-3)	O atom (OH) of Ser⁴²⁷
O of OH (C-3)	H atom (NH) of Lys⁴³¹

C = Carbon atom, H = Hydrogen atom, NH = Amine group, O = Oxygen atom, OH = Hydroxyl group.

^⁎

C-1 and C-3 show that hydrogen bonds are formed on OH groups of C atoms number 1 and number 3 (the order of C atoms refers to Figure 1).