Figure 5.

Proteome analyses of mice challenged with LPS. The total protein was isolated from the right lung lobes (n = 3 per experimental group) and proteome analyses were performed as described in the methods section. Principal component analyses of the regulated proteins showing separated groups of the replicate analyses (A). The volcano plots display the up- and down-regulated proteins (B). X-axes give the ratios of the mean protein intensities as log₂-values. Y-axes show the –lg of the p-values. The proteins upregulated in the LPS-treated samples are shown in red, and proteins downregulated in the LPS samples are shown in green. Some selected proteins are indicated by the gene name.