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. 2020 Jan 29;21(3):858. doi: 10.3390/ijms21030858

Figure 1.

Figure 1

Study schematic. Genomic DNA from patients at our institution who received allogeneic hematopoietic stem cell transplant between January 11, 2011 and May 31, 2016 (n = 252) was used to test associations between three single nucleotide polymorphisms (SNPs) in CYP3A4/5 and three SNPs in ABCB1 with pharmacokinetics and pharmacodynamics endpoints. Abbreviations: aGVHD, acute graft versus host disease; BMT, bone marrow transplant; HSCT, hematopoietic stem cell transplant; LTFU, lost to follow-up; PO, oral; UNC, University of North Carolina.