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CXCR-4. CXCR-4 mRNA expression (A) in vitro following inflammatory and hypoxic incubation, and (B) in vivo at different timepoints. (C) Association between LLS and CXCR4 mRNA expression (n-fold change) at 3883 m after 24 h. ** p < 0.01 vs. baseline (Munich 520 m a.s.l. or normoxic control in vitro), ° p ≤ 0.05 vs. prior time point in vivo. CXCR4=C-X-C chemokine receptor type 4.
