Table 2.
Characteristics of study subjects at inclusion and after being treated with auto-CPAP therapy.
| Characteristics | Subjects with OSA (n=139) | p | ||
|---|---|---|---|---|
| At inclusion | After 3 months treatment with auto-CPAP | After 6 months treatment with auto-CPAP | ||
| Number of subjects | 139 | 136 | 134 | |
| Anthropometric parameters | ||||
| Age, years | 51.3±16.4 | 51.6±15.8 | 51.9±16.7 | NS°,#,^ |
| Male/female, ratio (n) | 3.2 (106/33) | 3.3 (105/31) | 3.4 (104/30) | NS°,#,^ |
| BMI, kg/m2 | 28.4±3.8 | 27.6±4.3 | 27.3±3.9 | NS°,#,^ |
| Neck circumference, cm | 38.2±6.4 | 38.1±5.8 | 38.2±5.9 | NS°,#,^ |
| Abdomen circumference, cm | 85.7±11.6 | 84.6±12.4 | 84.3±11.3 | NS°,#,^ |
| Clinical symptoms - Blood pressures | ||||
| SBP, mmHg | 152±28 | 134±16 | 133±15 | <0.05°,#; NS^ |
| DBP, mmHg | 94±12 | 82±8 | 84±9 | <0.05°,#; NS^ |
| Epworth scores, (0-24) | 18.4±6.3 | 12.6±4.5 | 8.8±4.6 | <0.05°,^; <0.01# |
| Pichot scores*, (0-32) | 28.3±4.5 | 25.4±4.7 | 21.2±5.3 | NS°; <0.01#; <0.05^ |
| Biological parameters | ||||
| Glucose, mmol/L | 6.6±0.9 | 6.2±1.0 | 5.6±0.8 | NS°,^; <0.05# |
| Total cholesterol, mmol/L | 6.3±1.0 | 6.1±1.2 | 5.4±1.1 | NS°,^; <0.05# |
| LDL cholesterol, mmol/L | 4.1±0.8 | 3.8±0.7 | 3.5±0.9 | NS°,^; <0.05# |
| Triglycerides, mmol/L | 2.7±0.5 | 2.6±0.7 | 2.6±0.6 | NS°,#,^ |
| OSA parameters | ||||
| AHI, numbers/h | 39±7 | 12±6 | 7±3 | <0.001°,^; <0.05# |
| Auto-CPAP tolerance | ||||
| Acceptance rate, % | 100 | 97.8 | 96.4 | NS°,#,^ |
| Interface | ||||
| Nasal mask | 61.8 | 52.9 | 50.7 | <0.05°,#; NS^ |
| Full mask | 38.2 | 47.1 | 49.3 | <0.05°,#; NS^ |
OSA, obstructive sleep apnea; CPAP, continuous positive pressure; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL, low-density lipoprotein; AHI, apnea-hypopnea index
*Pichot scores for tiredness
°3rd month vs inclusion
#6th month vs inclusion
^6th month vs 3rd month.