Figure 2.
Inhibitory effect of Rb1, Rb2, Rc, Rd, compound K, Rg3, Rh2, PPD, PPT, Re, Rg1, and Rh1 on the OATP1B1-mediated transport of [3H]estrone-3-sulfate (ES). OATP1B1-mediated ES uptake were calculated by subtracting 0.1 μM [3H]ES uptake in HEK293-mock cells from 0.1 μM [3H]ES uptake in HEK293-OATP1B1 cells. Data are the mean ± SD from triplicate measurements.