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(A) Uptake of valsartan (5 μM) by HEK293-mock cells and HEK293 cells expressing OATP1B1 and OATP1B3. Inhibitory effect of rifampin on the (B) OATP1B1- and (C) OATP1B3-mediated uptake of valsartan. Data points represent the mean ± SD from triplicate measurements. *p < 0.05 compared with HEK293-mock cells.
