Skip to main content
. 2020 Jan 31;25(3):622. doi: 10.3390/molecules25030622

Table 3.

Pharmacokinetic parameters of ginsenosides in the rat plasma after 1-week repeated administration of red ginseng extract (RGE).

Ginsenosides Pharmacokinetic Parameters
AUC (ng∙h/mL) Cmax (ng/mL) Tmax (h) MRT (h) T1/2 (h)
Rb1 454.57 ± 111.33 17.84 ± 2.34 3.33 ± 1.15 17.13 ± 2.09 16.87 ± 5.81
Rb2 282.80 ± 58.90 10.02 ± 1.04 3.33 ± 1.15 18.61 ± 1.43 30.19 ± 5.48
Rc 320.75 ± 97.23 11.67 ± 2.49 3.33 ± 1.15 18.35 ± 1.89 24.24 ± 7.51
Rd 163.83 ± 39.07 5.10 ± 0.74 2.17 ± 1.76 20.84 ± 1.68 43.49 ± 17.54
PPD 542.01 ± 141.09 20.56 ± 9.47 16.50 ± 12.48 21.56 ± 3.31 26.95 ± 18.33
PPT 429.91 ± 105.75 16.97 ± 8.99 16.50 ± 12.48 23.12 ± 2.26 46.38 ± 13.27

Data represent mean ± SD of four rats per group. AUC: area under the plasma concentration-time curve from 0 to 48 h Cmax: maximum plasma concentration; Tmax: time to reach Cmax; MRT: Mean residence time; T1/2: Half-life.