Scheme 4.
Reagents and Conditions: (a) NaOMe, MeOH, rt, 2 h, 82–87%; (b) K2CO3, alkyl iodide, DMF, rt, 20 h; and (c) NaOMe, MeOH, rt, 3 h, 28–33% for two steps.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.