. Author manuscript; available in PMC: 2021 Jan 1.

Published in final edited form as: Mov Disord. 2019 Sep 30;35(1):116–133. doi: 10.1002/mds.27862

TABLE 4.

Reproducibility parameters of the MDS-NMS

Domain	Test-retest (n = 123)		Interrater (n = 164)		Precision SEM
Domain	Kappa_w	ICC	Kappa_w	ICC	Precision SEM
A. Depression	0.45–0.74	0.73	0.91–1.0^b	0.99	4.91
B. Anxiety	0.39–0.66	0.66	0.93–0.99	0.99	4.53
C. Apathy	0.48–0.53	0.62	0.89–1.0^b	0.99	4.04
D. Psychosis	0.26–0.68	0.66	0.98–1.0^b	0.99	2.35
E. IC and related disorders	0.36–0.94	0.50	0.94–1.0^b	1.0	1.57
F. Cognition	0.58–0.74	0.74	0.94–0.98	0.99	5.80
G. Orthostatic hypotension	0.58–0.62	0.56	0.94–0.95	0.97	2.61
H. Urinary	0.68–0.78	0.78	0.96–0.99	0.99	4.52^a
I. Sexual	0.59–0.71	0.70	0.96–1.0^b	0.99	4.12
J. Gastrointestinal	0.59–0.79	0.77	0.98–0.99	0.99	3.37^a
K. Sleep and wakefulness	0.56–0.74	0.81	0.94–0.99	0.97	4.74^a
L. Pain	0.45–0.73	0.75	0.99	1.0	4.78^a
M. Other	0.65–0.86	0.85	0.95–0.98	0.98	4.39^a
MDS-NMS total score	—	0.84	—	1.0	25.30^a
NMF change	0.48–0.68	0.76	0.90–0.99	0.99	2.61
Time in off	0.70	—	0.97	—
NMF total score	—	0.70		1.0	7.06

SEM, standard error of measurement.

SEM < ½SD_pooled.

Rounded figures when weighted kappa value was >0.999.