Table A2.

Confusion matrix for logistic regression of PBMC and lymphoblast ME/CFS biomarkers using a randomly selected training and test subcohorts.

Subcohort	Clinical Group	Actual Count	Test Class		% Error	Statistics
			ME/CFS	Control
PBMC cell death after 48 h in culture
Training	ME/CFS	46	41	5	10.9	χ2	17.0
	Control	25	10	15	40.0	p	3.8 × 10−5
	TOTAL	71	51	20	21.2	Fisher p = 2.1 × 10−5
Test	ME/CFS	11	11	0	0	χ2	6.39
	Control	8	3	5	37.5	p	0.012
	TOTAL	19	14	5	15.8	Fisher p = 4.8 × 10−3
Lymphoblast Seahorse respirometry
Training	ME/CFS	37	34	3	8.1	χ2	16.6
	Control	17	6	11	35.3	p	4.6 × 10−5
	TOTAL	54	40	14	16.6	Fisher p = 3.1 × 10−5
Test	ME/CFS	12	10	2	16.7	χ2	4.22
	Control	3	0	3	0.0	p	0.04
	TOTAL	15	10	5	13.3	Fisher p = 0.022
Lymphoblast TORC1 activity
Training	ME/CFS	34	30	4	11.8	χ2	10.65
	Control	19	8	11	42.1	P	1.1 × 10−3
	TOTAL	53	38	15	22.6	Fisher p = 9.1 × 10−4
Test	ME/CFS	10	9	1	10.0	χ2	1.59
	Control	3	1	2	33.3	p	0.21
	TOTAL	13	10	3	15.3	Fisher p = 0.11
Combined tests
Training	ME/CFS	22	21	1	4.5	χ2	20.9
	Control	11	1	10	9.1	p	4.9 × 10−6
	TOTAL	33	22	11	6.1	Fisher p = 1.3 × 10−6
Test	ME/CFS	7	6	1	14.3	χ2	3.35
	Control	3	0	3	0.0	p	0.067
	TOTAL	10	6	4	10.0	Fisher p = 0.033