FoxOs |
Forkhead box class O family member proteins |
LPS |
Lipopolysaccharide |
TNF-α |
Tumor necrosis factor α |
MSCs |
Mesenchymal stem cells |
Runx2 |
Runt-related transcription factor 2 |
ALP |
Alkaline phosphatase |
OCN |
Osteocalcin |
CFU |
Colony forming unit |
PPARγ |
Peroxisome proliferator-activated receptor γ |
PPREs |
PPAR-response elements |
PCNA |
Proliferating cell nuclear antigen |
ROS |
Reactive oxygen species |
FABP4 |
Fatty acid-binding protein 4 |
4-HNE |
4-hydroxynonenal |
ATF4 |
Activating transcription factor 4 |
BFR |
Bone formation rate |
HSC |
Hematopoietic stem cell |
Gpx-1 |
Glutathione peroxidase 1 |
M-CSF |
Macrophage-colony stimulating factor |
RANK |
Receptor activator of NF-κ B |
RANKL |
Receptor activator of NF-κ B ligand |
BMMCs |
Bone marrow mononuclear cells |
NFATc1 |
Nuclear factor of activated T cells 1 |
Akt |
Protein kinase B |
SIRT-1 |
Sirtuin 1 |
TRAP |
Tartrate-resistant acid phosphatase |
MAPKs |
Mitogen-activated protein kinases |
NF-κB |
Nuclear factor kappa-B |
HO-1 |
Hemeoxygenase-1 |
Mst 1 |
Mammalian Sterile 20-like kinase 1 |
OPG |
Osteoprotegerin |
AP-1 |
Activator protein 1 |
PI3K |
phosphoinositide 3-kinase |
OA |
Osteoarthritis |
PTP1B |
Protein tyrosine phosphatase 1B |
CTKO |
Chondrocyte triple knock-out |
PTEN |
Phosphatase and tensin homolog deleted on chromosome ten |