Figure 3.

Combination therapy of Cloudman S91 tumor bearing male DBA/2 mice with anti-PD-1 mAb and two doses RIT with ²¹³Bi-h8C3 mAb. The mice in groups of five were treated with: (a) two doses of 400 µCi ²¹³Bi-h8C3 given on Days 8 and 15 and three doses of anti-PD-1 mAb given on Days 8, 11, and 15; (b) two doses of 400 µCi ²¹³Bi-h8C3 given on Days 9 and 16; (c) combined plot for all treatment groups. Each tumor volume curve represents a single animal. Blue and red arrows indicate the injection of anti-PD1 antibody and RIT, respectively.