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. 2020 Feb 11;23(3):100894. doi: 10.1016/j.isci.2020.100894

Figure 1.

Figure 1

Hippocampal Neurons Innervated Three Major GABAergic Neuron Types in the mPFC

(A) Monosynaptic rabies virus tracing strategy.

(B) Injection site at mPFC.

(C) Enlarged image boxed in (B), showing the AAV, RV, and double labeling neurons. The double labeling neurons were defined as starter cells.

(D and E) Immunostaining against parvalbumin and somatostatin at the injection sites. The TVA-mCherry and EGFP expressed neurons in PV-Cre mice and SST-Cre mice were parvalbumin and somatostatin positive, respectively.

(F) Input neurons from hippocampus.

(G) Distribution of hippocampal neurons targeted three types of GABAergic neuron in the mPFC. Scale bars in (B) and (F) are 1 mm; scale bar in (C) is 200 μm; scale bars in (D) and (E) are 50 μm.