AD	Autosomal dominant
AR	Autosomal recessive
BASC	BRCA1-associated genome surveillance complex
BC	Breast cancer
cAMP	Cyclic adenosine monophosphate
DGC	Diffuse-type gastric cancer
DSB	Double-strand break
ERK	Extracellular signal-regulated kinase
FA	Fanconi anemia
GTP	Guanosine triphosphate
HBOC	Hereditary Breast and Ovarian Cancer
HDGC	Hereditary Diffuse Gastric Cancer syndrome
HR	Homologous recombination
LBC	Lobular breast cancer
LFS	Li-Fraumeni syndrome
LPV	Likely-pathogenic variant
LS	Lynch syndrome
MAPK	Mitogen-activated protein kinase
MBC	Male breast cancer
MMR	Mismatch repair
MRI	Magnetic resonance imaging
MRN	MRE11-RAD50-NBS1 complex
NA	Not assessed
NBS	Nijmegen breakage syndrome
NCCN	National Comprehensive Cancer Network
NGS	Next-Generation Sequencing
OC	Ovarian cancer
PARP	Poly adenosine-diphosphate ribose polymerase
PJS	Peutz-Jeghers syndrome
PML	Promyelocytic leukemia protein
PV	Pathogenic variant
RR	Relative risk
RRM	Risk-reducing mastectomy
RRSO	Risk-reducing salpingo-oophorectomy
TCGA	The Cancer Genome Atlas
VUS	Variant of uncertain significance