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Cell body area of Iba-1+ cells in the outer plexiform layer (OPL), in 3xTg-AD, and in age-matched control mice in the different retinal zones (inferior, nasal, superior, and temporal), as well as in the total retina. A total of 576 microglial cells were measured for each study group (3xTg-AD and control). Histograms show the mean cell body area (± standard deviation, SD) of the Iba-1+ cells. Statistically significance indicators: ** p < 0.01.
