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. 2020 Feb 6;21(3):1071. doi: 10.3390/ijms21031071

Figure 2.

Figure 2

Inhibitors of chondrocytes dysfunction and corresponding targeting pathways. Resveratrol interferes with lymphotoxin α signaling, necrostatin-1 inhibits necroptosis pathway, hyaluronan blocks MAPK pathway, and paclitaxel suppresses AP-1 activity which contribute to chondrocyte dysfunction in rheumatoid arthritis.