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The association between serine protease activity in the SC in lesions of AD patients and medical treatments. Trypsin- or chymotrypsin-like serine protease activity in lesions were compared with and without topical corticosteroid (A,B), topical tacrolimus (C,D), oral antihistamine (E,F), oral corticosteroid (G,H) and oral cyclosporine therapies (I,J). * p < 0.05.
