Table 5.
Potential use of nanoparticles in immunotherapy.
| Nanoparticle | Purpose | Reference |
|---|---|---|
| Dynabeads with anti-CD3 and anti-CD28 | T-cell expansion | [164] |
| IL-2 packed in poly(lactide-co-glycolide) nanoparticles together with magnetite | T-cell expansion | [165] |
| T-cell receptor labelled with gold | T-cell tracking | [166] |
| Hydrogel composed of poly(ethyleneglycol)-g-chitosan | Control release of T-cell | [167] |
| Poly(lactic-co-glycolic) acid nanoparticles loaded with indocyanine green | Photothermal therapy | [168] |
| NP formed of poly (lactic-co-glycolic) acid | Antigen binding | [169] |
| Cell-membrane derived vesicles | Therapy | [170] |
| Gold nanostars | Photothermal therapy | [171] |
| NLG919/IR780 micelles | Photothermal therapy | [172] |
| Gold nanoshells | Photothermal therapy | [173] |
| Nanodiscs | Presentation of antigens | [174] |
| Lipid/calcium/phosphate nanoparticle | Delivery of mRNA-encoding MUC1 | [175] |
Note: IL-2 = interleukin 2; NP = nanoparticle; MUC1 = mucin 1, cell surface associated.