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Cerebral microvascular amyloid accumulation in Tg-SwDI mice. Representative brain sections from 9-month-old Tg-SwDI mice stained with thioflavin S to identify fibrillar microvascular amyloid (green) and immunolabeled with an antibody to collagen IV to identify cerebral blood vessels (red). Microvascular amyloid deposits are observed in the cortex (A), subiculum (B), and thalamus (C). Scale bars = 50 µm.
