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. 2020 Jan 21;21(3):704. doi: 10.3390/ijms21030704

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Alterations in biochemical properties of rabbit AH under conditions of LIRD without treatment (black), in the course of treatment with Nepafenac (red), after premedication with SkQ1 (blue), and in the course of the therapy using the combination of the both drugs (green). The animals were illuminated with intense visible light (30,000 lx) for 3 h (the course of the illumination is shown as a gray box). The AH samples were collected before (norm) and immediately after (3 h) the illumination as well as on 1, 3, and 7 day post-exposure. The samples were analyzed for TNF-α and malondialdehyde content as well as total antioxidant activity (in Trolox equivalent) and activity of glutathione peroxidase and superoxide dismutase using the respective assays. * p > 0.05 as compared to the parameters of AH of the untreated illuminated animals.