FIG 7.

Virulence tests of Δaat tachyzoites in mice. (A and B) Body weight (%) (A) and survival rate (B) during ΔRHaat infection. Mice were infected by i.p. injection with 100 RH (n = 11), ΔRHaat (n = 11), or ComRHAAT (n = 6) tachyzoites. (C) Body weight during ΔPLKaat infection. Six mice were infected with 10,000, 30,000, and 50,000 tachyzoites by i.p. injection. (D) Survival rate of PLK AAT deficiency parasite infection in mice. Survival curves of mice infected with ΔPLKaat tachyzoites were noted until day 30. *, P < 0.05; **, P < 0.01, log-rank (Mantel-Cox) test.