TABLE 4.
FEV1 by treatment group
| Visit | Mean (SD) of FEV1 (liters) |
||||
|---|---|---|---|---|---|
| Part 1 (healthy subjects) |
Part 2 (cystic fibrosis subjects) |
||||
| 16 mg (n = 6) | 32 mg (n = 6) | 80 mg (n = 6) | 32 mg (n = 6) | 80 mg (n = 6) | |
| Screening | 4.605 (0.639) | 4.518 (0.466) | 4.693 (0.213) | 1.967 (0.350) | 2.280 |
| Predose | 4.503 (0.637) | 4.418 (0.414) | 4.587 (0.268) | 1.872 (0.370) | 1.843 (0.354) |
| 30 min | 4.543 (0.685) | 4.362 (0.410) | 4.337 (0.303) | ||
| 1 h | 1.720 (0.449) | 1.620 (0.476) | |||
| 8 h | 1.687 (0.436) | 1.648 (0.419) | |||
| 24 h | 1.913 (0.455) | 1.750 (0.398) | |||
| Follow-up | 4.725 (0.843) | 4.370 (0.502) | 4.500 (0.393) | 2.220 () | 1.838 (0.473) |