FIG 3.

Visual predictive check (VPC) for isoniazid, pyrazinamide, and ethambutol concentration versus time (time since the dose), stratified by pregnancy. The circles represent the original data, the dashed and solid lines are the 5th, 50th, and 95th percentiles of the original data, and the shaded areas are the corresponding 95% confidence intervals for the same percentiles, as predicted by the model. An appropriate model is expected to have most observed percentiles within the simulated confidence intervals.