FIG 1.

Use of alignment to assign SANC-based amino acid residue numbers. Positions corresponding to insertions and deletions are indicated in bold. ADC-7 adds residues 0, 204a, and 262 and deletes residues 245 and 304 to 306. ADC-8 adds residues 0 to 0d and 262 to 267 and deletes residue 245. BUT-1 adds residue 0. PDC-1 adds residues 125a, 204a, and 362 to 370 and deletes residue 245. For reference, signal sequences are highlighted in yellow, S⁶⁴XXK in green, Y¹⁵⁰XN in blue, and K³¹⁵(S/T)G in red.