FIG 1.

Survival curves in mice inoculated intravenously with C. auris and treated with vehicle control, fluconazole 20 mg/kg orally (p.o.) once a day (QD), or caspofungin 10 mg/kg intraperitoneally (i.p.) QD (A) or T-2307 at doses of 0.75 mg/kg, 1.5 mg/kg, or 3 mg/kg subcutenously QD (B). Treatment started 1 day postinoculation and continued for 7 days. Mice were then followed off therapy until day 21 postinoculation (14 days after therapy stopped). Black square, vehicle (untreated) control; white circle, fluconazole 20 mg/kg; black circle, caspofungin 10 mg/kg; inverted gray triangle, T-2307 0.75 mg/kg; gray rectangle, T-2307 1.5 mg/kg; gray triangle, T-2307 3 mg/kg. n = 10 mice per group.