TABLE 3.

Isavuconazole dosage and PK data

Characteristic or parameter	Value
No. (%) of patients receiving an ISA loading dose	13 (44.8)
No. (%) of patients receiving the following ISA dose:
100 mg/day	7 (24.1)
200 mg/day	22 (75.9)
Median (range) treatment duration (days) for those ages:	75.5 (6–523)
1 to <6 yr	46 (12–231)
6 to <12 yr	86 (6–153)
12 to <18 yr	80 (6–523)
Median (range) dose/kg/day (mg/kg) for patients with a body wt of:	4 (2.50–6.67)
<30 kg	4.55 (3.57–6.67)
>30 kg	4 (2.50–5.71)
Median (range) Ctrough (mg/liter) for patients with a body wt of:	4.91 (2.15–8.54)
<30 kg	1.1 (0.73–2.15)
>30 kg	5 (2.48–8.54)
Median (range) concn/dose (in kg) for patients with a body wt of:	1.13 (0.47–3.42)
<30 kg	0.75 (0.47–1.38)
>30 kg	1.38 (0.71–3.42)
Median (range) AUC0–24 (mg·h/liter)	153.16 (86.31–169.45)