TABLE 1.
Cefazolin and oxacillin MICs in standard and alternative medium types used in the pharmacodynamic model
| Medium or media | MIC (mg/liter) |
|||||||
|---|---|---|---|---|---|---|---|---|
| CFZ |
OXA |
|||||||
| 11-11 | MW2 | COL | BMC-1001 | 11-11 | MW2 | COL | BMC-1001 | |
| CAMHB-Tris | 16 | 8 | 256 | 256 | 64 | 32 | 512 | 256 |
| CAMHB-Tris + 2% NaCl | 16 | 8 | 256 | 256 | 64 | 32 | 512 | 256 |
| CAMHB-Tris + 25 mM NAHCO3 | 4 | 8 | 256 | 256 | 4 | 32 | 512 | 256 |
| CAMHB-Tris + 44 mM NAHCO3 | 1 | 1 | 256 | 256 | 1 | 2 | 512 | 256 |
| RPMI 1640 + 10% LB medium | 1 | 2 | 32 | 8 | 1 | 1 | 64 | 4 |