Figure 5.

Tumor and Effector Cell Dynamics in Response to RT Fractionation Schemes with Different Number of Fractions

(A–D) Time-evolution of tumor radius and effector cells during and after RT for different functional degrees of tumor-associated vascularity (B) and fractionation schemes of 15 and 35 daily fractions at Gy/day and 5 days/week. Model simulations were performed with $\eta =8.0\times {10}^5$ cells day⁻¹, ${\lambda }_M=1.15$ day⁻¹, and a tumor size at time of RT equal to $R=15$ mm, unless indicated otherwise.

The remaining parameter values were as in Table S1 [Parameter values considered in model simulations].