Table 2.
Significance of association between SNPs on chromosome 1 and tibial breaking strength in hens at 70 weeks of age
| Marker name | GalGal6 chr 1 position (bp) | F statistic | P value | Heterozygote effect (Newton) | Homozygote effect (Newton) |
|---|---|---|---|---|---|
| Ost92365348 | 90,332,842 | 0.22 | 0.802 | ||
| Ost99883015 | 97,883,872 | 1.6 | 0.203 | ||
| Ost101413556 | 99,395,470 | 2.04 | 0.131 | ||
| Ost106225194 | 104,084,042 | 7.45 | < 0.001 | 6.08 | 16.02 |
| Ost106460620 | 104,314,846 | 2.88 | 0.057 | ||
| Ost106823022 | 104,678,816 | 3.85 | 0.022 | 12.77 | 2.62 |
| Ost106940170 | 104,834,987 | 4.9 | 0.008 | 6.336 | 17.15 |
| Ost107389494 | 105,280,127 | 6.3 | 0.002 | 13.2 | − 1.65 |
| Ost107766125 | 105,655,660 | 5.58 | 0.004 | 12.61 | 4.83 |
| Ost108015093 | 105,901,013 | 5.59 | 0.004 | 12.69 | 4.82 |
| Ost109151638 | 107,036,767 | 3.17 | 0.042 | − 7.75 | − 16.75 |
| Ost109151769 | 107,036,898 | 3.17 | 0.042 | 9.00 | 16.75 |
| Ost110373245 | 108,261,209 | 3.18 | 0.042 | − 0.58 | − 8.29 |
| Ost110455031 | 108,342,396 | 5.49 | 0.004 | 6.59 | 18.46 |
| Ost112374543 | 110,246,492 | 3.51 | 0.03 | − 2.98 | − 12.63 |
| Ost112522587 | 110,393,717 | 6.34 | 0.002 | 9.92 | 16.55 |
| Ost113740421 | 111,546,531 | 1.59 | 0.205 | ||
| Ost113743229 | 111,549,338 | 1.29 | 0.276 | ||
| Ost114648871 | 112,392,632 | 0.99 | 0.372 | ||
| Ost115611476 | 113,329,344 | 3.66 | 0.026 | − 3.8 | − 11.13 |
| Ost115617544 | 113,335,412 | 0.44 | 0.647 | ||
| Ost115655839 | 113,373,156 | 2.47 | 0.085 | ||
| Ost115861595 | 113,578,876 | 1.97 | 0.14 | ||
| Ost115862305 | 113,579,586 | 1.78 | 0.17 | ||
| Ost115865281 | 113,582,562 | 1.4 | 0.248 | ||
| Ost115866264 | 113,583,545 | 0.16 | 0.92 | ||
| Ost121757410 | 119,732,454 | 0.2 | 0.821 | ||
| Ost121237272 | 119,214,984 | 6.19 | 0.013 | − 7.67 | |
| Ost126455926 | 124,863,293 | 0.27 | 0.601 | ||
| Ost129219873 | 126,721,130 | 5.68 | 0.004 | − 46.2 | − 61.66 |
| Ost134239048 | 131,424,865 | 0.14 | 0.872 | ||
| Ost134239237 | 131,425,054 | 0.14 | 0.872 |
F values were obtained by REML analysis with body weight, hatch, total eggs and eggs in the 3 days before death as fixed effects, and sire and dam as random effects. Effect sizes are quoted relative to the reference homozygote only for the SNPs that had a nominal significance level lower than 0.05. If corrected for multiple testing and taking the identification of seven blocks containing 23 SNPs using Haploview [40] into account, then the significance after Bonferroni correction should be set at 0.003. The SNPs passing this threshold are in italic characters. The additive effect represents half that of the homozygote reference