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. 2020 Feb 24;18:101. doi: 10.1186/s12967-020-02268-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — ABAT and ALDH6A1 expression in ccRCC clinical samples. a 50 pairs of ccRCC organizations were used to detect ABAT mRNA levels by quantitative-PCR. b Paired analysis of ABAT mRNA detection; p < 0.0001. c For 50 pairs of ccRCC samples, quantitative PCR was used to detect ALDH6A1 mRNA levels. d Paired analysis of ALDH6A1 mRNA detection; p < 0.0001. e Immunohistochemical detection of ABAT. f Box plot depicting ABAT levels as assessed by IHC in 29 paired ccRCC samples; p < 0.0001. g Immunohistochemical detection of ALDH6A1. h Box plot depicting ALDH6A1 levels as assessed by IHC in 29 paired ccRCC samples; p < 0.0001