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. 2020 Feb 21;20:83. doi: 10.1186/s12887-020-1964-y

Table 3.

Rates of change in outcomes estimated by mixed effects model by sex and program status

Rate of change of outcome (per year)
Males & Females Males Females
Outcome of each model Group indicator a Rate of change (unit/year) Standard error p-value vs. Ca Rate of change (unit/year) Standard error p-value vs. Ca Rate of change (unit/year) Standard error p-value vs. Ca
BMI z-score B + P 0.02322 0.02401 0.1292 0.03198 0.04089 0.1886 0.01316 0.02422 0.4654
B 0.04661 0.03001 0.3969 0.08685 0.04747 0.6667 0.00321 0.03359 0.3984
C 0.08362** 0.03161 0.11626* 0.04888 0.04514 0.03636
Percent body fat (%) B + P 1.3784** 0.4691 0.2319 1.7398** 0.5517 0.0265 1.1805* 0.4845 0.8099
B 1.8076** 0.5588 0.1021 2.2980*** 0.6407 0.0076 1.8399** 0.6219 0.6313
C 0.4771 0.5882 −0.1397 0.6306 1.3871 0.7070
Calcium-rich food knowledge score B + P 0.4788*** 0.0855 0.9342 0.4306** 0.1425 0.8080 0.4897*** 0.1151 0.7887
B 0.7524*** 0.1097 0.0680 0.7004*** 0.1660 0.3458 0.7848*** 0.1572 0.1333
C 0.4672*** 0.1104 0.4827** 0.1593 0.4345* 0.1706
Physical activity knowledge score B + P 32.88*** 8.27 0.5947 35.96** 12.58 0.5123 29.99** 10.95 0.9289
B 44.58*** 10.56 0.2088 40.46** 15.14 0.4153 48.81** 14.72 0.3449
C 25.70* 10.64 23.43 14.33 28.26 15.92
Calcium-rich food preference score B + P 0.1084 0.0619 0.8224 0.1353 0.0938 0.5823 0.0948 0.0835 0.8278
B 0.1088 0.0795 0.8375 0.0668 0.1115 0.9517 0.1313 0.1144 0.9816
C 0.0857 0.0800 0.0575 0.1053 0.1274 0.1240
Total calcium intake B + P −9.58 42.35 0.4939 −14.39 55.73 0.5383 −22.70 46.75 0.6603
B 15.62 52.08 0.7695 −33.04 65.98 0.4407 47.57 62.68 0.7301
C 37.75 54.57 37.68 63.32 14.79 71.10
Trimmed calcium intake (< 2500 for age up to 9, < 3000 for age > =9) B + P −6.44 38.28 0.3339 −20.00 50.79 0.2724 −7.26 44.34 0.7929
B 3.87 47.67 0.4653 −35.06 51.23 0.2377 24.60 59.38 0.9050
C 54.06 49.38 64.94 57.88 13.89 67.01
MET score B + P 1.8873** 0.6772 0.0026 1.6754 1.0115 0.0039 2.0405* 0.8800 0.3259
B 0.8487 0.5874 0.0596 1.7086 1.2161 0.0076 −0.1833 1.1811 0.6910
C −1.4592 0.8682 −2.8420* 1.1566 0.5103 1.2797
WBF score B + P 0.4746*** 0.1349 0.0019 0.5125* 0.2052 0.0010 0.4260* 0.1753 0.5584
B 0.2317 0.1708 0.0679 0.4448 0.2454 0.0046 0.0037 0.2349 0.4753
C −0.2141 0.1731 − 0.5335* 0.2339 0.2445 0.2550
Grip strength (kg) B + P 1.2406*** 0.1461 0.6682 1.0568*** 0.1802 0.9395 1.3980*** 0.1709 0.4730
B 1.0055*** 0.1787 0.6049 1.0356*** 0.2122 0.9988 1.0197*** 0.2244 0.6379
C 1.1391*** 0.1861 1.0361*** 0.2050 1.1789*** 0.2522
Vertical jump (in) B + P 0.6154*** 0.1473 0.6493 0.6276*** 0.1773 0.8487 0.5810** 0.1747 0.3824
B 0.2651 0.1780 0.0759 0.0243 0.2089 0.0601 0.5269* 0.2237 0.3414
C 0.7233*** 0.1857 0.5761** 0.2027 0.8497** 0.2538
Bone stiffness B + P 0.5682 0.8032 0.0506 −1.6887 1.4825 0.4189 2.0487* 0.8608 0.0995
index (3 groups) B −0.2319 1.1187 0.2368 −4.0010 2.0555 0.8523 2.0957 1.1986 0.1386
C −2.0669 1.0574 −3.5066* 1.6495 −0.5761 1.3078
Bone stiffness B + P/B 0.3026 0.6527 0.0603 −2.4862* 1.2067 0.6204 2.0757** 0.6990 0.0797
index (2 groups) C −2.0670 1.0584 −3.5101* 1.6554 −0.5754 1.3078

Abbreviations: B + P BONES + Parent, B BONES, C Control, BMI body mass index, MET metabolic equivalent time, WBF weight-bearing factor

Adjusted for time point, baseline age, and race/ethnicity (white, black, Hispanic, others); adjusted for individual nested within after-school program as cluster effects

In total, 2476 observations were made in the three time points. Numbers of observations used in the above analysis range from 1828 (74%) to 1902 (77%) for all the outcomes except bone stiffness. For bone stiffness, the number of observation used in the analysis is 981 (40%)

ap vs. C: p-value of the difference between the slopes of the intervention (B + P or B) and the control group

* p < 0.05; ** p < 0.01; *** p < 0.001; these p-values indicate if the rate of change is significantly different from zero